ISOTEC® Stable Isotopes Products for MRI/MRS and PET Imaging

ISOTEC® Stable Isotopes Products for Solid State NMR

MRI/MRS: Use of Isotopes in Hyperpolarization

The single greatest impediment to the use of nuclear magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) in vivo is its limited sensitivity . Hyperpolarization promises enhanced magnetic resonance, with signal amplification up to 200,000‐fold greater than we have today, this technology will detect attomoles to nanomoles of isotopically labeled specific disease markers in ...

MRI/MRS Use of Isotopes in Hyperpolarization: Biomedical Applications

The single greatest impediment to the use of nuclear magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) in vivo is its limited sensitivity . Hyperpolarization promises enhanced magnetic resonance, with signal amplification up to 200,000‐fold greater than we have today, this technology will detect attomoles to nanomoles of isotopically labeled specific disease markers in ...

Stable Isotopes: An Approach to Quantifying the Conversion of Carbohydrate to Fat in Humans

Using stable isotopes in metabolic research with an emphasis on C, N or deuterated compounds offers a safe and reliable tool for metabolic profiling. Isotopic tracer studies coupled with the use of LC/MS, GC/MS and NMR allows researchers to investigate specific pathways involving glucose, fatty acids, amino acids and proteins. Doubly labeled water also continues as a valuable tool in energy exp...

Multimodal imaging of tumor response to sorafenib combined with radiation therapy: comparison between diffusion-weighted MRI, choline spectroscopy and 18F-FLT PET imaging.

The purpose of this study was to determine the value of different imaging modalities, that is, magnetic resonance imaging/spectroscopy (MRI/MRS) and positron emission tomography (PET), to assess early tumor response to sorafenib with or without radiotherapy. Diffusion-weighted (DW)-MRI, choline (1)H MRS at 11.7 T, and (18)F-FLT PET imaging were used to image fibrosarcoma (FSaII) tumor-bearing m...